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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
34.55
Human Site:
Y239
Identified Species:
50.67
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
Y239
H
R
F
K
V
Y
N
Y
K
S
P
T
F
C
E
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y239
H
R
F
K
V
Y
N
Y
K
S
P
T
F
C
E
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
Y702
H
R
F
K
V
H
N
Y
M
S
P
T
F
C
D
Dog
Lupus familis
XP_849292
706
81555
Y239
H
R
F
K
V
Y
N
Y
K
S
P
T
F
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
Y239
H
R
F
K
V
Y
N
Y
K
S
P
T
F
C
E
Rat
Rattus norvegicus
Q9WTQ0
707
81732
Y239
H
R
F
K
V
Y
N
Y
K
S
P
T
F
C
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
Y239
H
R
F
K
V
Y
N
Y
K
S
P
T
F
C
E
Chicken
Gallus gallus
NP_001006133
699
80179
Y236
H
R
F
K
V
Y
N
Y
M
S
P
T
F
C
D
Frog
Xenopus laevis
Q7LZQ8
671
76506
S215
K
T
K
T
I
K
C
S
L
N
P
S
W
N
E
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
T221
I
K
C
C
L
N
P
T
W
N
E
T
F
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
K216
S
L
G
I
S
P
D
K
Q
Q
P
R
R
S
K
Honey Bee
Apis mellifera
XP_394743
624
71014
D211
F
R
Q
G
V
R
C
D
D
C
D
M
A
C
H
Nematode Worm
Caenorhab. elegans
P34722
704
80280
F245
H
R
F
K
T
Y
N
F
K
S
P
T
F
C
D
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
K210
L
S
S
I
E
K
D
K
K
L
P
P
G
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
N489
H
R
F
L
P
T
S
N
R
G
T
K
W
C
C
Red Bread Mold
Neurospora crassa
P87253
1142
127954
N533
H
R
F
I
P
F
S
N
L
T
A
N
W
C
C
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
80
100
N.A.
100
100
N.A.
100
86.6
13.3
13.3
N.A.
6.6
20
80
13.3
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
93.3
40
33.3
N.A.
26.6
20
93.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
7
0
7
7
0
% A
% Cys:
0
0
7
7
0
0
13
0
0
7
0
0
0
75
13
% C
% Asp:
0
0
0
0
0
0
13
7
7
0
7
0
0
0
19
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
44
% E
% Phe:
7
0
69
0
0
7
0
7
0
0
0
0
63
0
7
% F
% Gly:
0
0
7
7
0
0
0
0
0
7
0
0
7
0
7
% G
% His:
69
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
19
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
7
7
57
0
13
0
13
50
0
0
7
0
0
7
% K
% Leu:
7
7
0
7
7
0
0
0
13
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
13
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
7
57
13
0
13
0
7
0
7
0
% N
% Pro:
0
0
0
0
13
7
7
0
0
0
75
7
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
7
7
0
0
0
0
0
% Q
% Arg:
0
75
0
0
0
7
0
0
7
0
0
7
7
0
0
% R
% Ser:
7
7
7
0
7
0
13
7
0
57
0
7
0
7
0
% S
% Thr:
0
7
0
7
7
7
0
7
0
7
7
63
0
7
0
% T
% Val:
0
0
0
0
57
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
19
0
0
% W
% Tyr:
0
0
0
0
0
50
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _